Copyright (c) 1996,1997,1998
Institute for Biomedical Research. All rights reserved.
Redistribution and use in source
and binary forms, with or without modification, are permitted
provided that the following conditions are met:
We also request that use of this software
be cited in publications as
the above copyright notice, this list of conditions and
the following disclaimer in the documentation and/or
materials provided with the distribution.
of source code must also reproduce this information in
source code itself.
If the program is modified,
redistributions must include a notice (in the same
as above) indicating that the redistributed program is
identical to the version distributed by Whitehead
mentioning features or use of this software must
the following acknowledgment:
software developed by the Whitehead
The name of the Whitehead
Institute may not be used to endorse or promote products
derived from this software without specific prior
Steve Rozen, Helen J.
(1998) Primer3. Code available at
THIS SOFTWARE IS PROVIDED BY THE
WHITEHEAD INSTITUTE ``AS IS'' AND ANY EXPRESS OR IMPLIED
INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF
AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT
SHALL THE WHITEHEAD INSTITUTE BE LIABLE FOR ANY DIRECT,
INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT,
STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF
ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
The development of Primer3 and
the Primer3 web site was funded by Howard
Hughes Medical Institute
and by the National
Institutes of Health,
National Human Genome Research Institute.
(to David C. Page) and P50-HG00098 (to Eric S. Lander).
We gratefully acknowledge the support
Corporation, which provided the Alphas which were used
much of the development of Primer3, and of Centerline Software,
Inc., whose TestCenter memory-error, -leak, and test-coverage
checker we use regularly to discover and correct otherwise
errors in Primer3.
Original design of this
web site by Richard Resnick, who also is an author
of this site's documentation. Primer3's design is heavily based
on earlier implementations of similar programs: Primer 0.5
Lincoln, Mark Daly, and Eric S. Lander) and Primer v2
Resnick). Lincoln Stein championed the use of
the Boulder-IO format and the idea of making the Primer3 engine
a software component.